An AlphaFold3 model of a bacterial enzyme bound to a chemical.Credit: Isomorphic Labs Since the powerhouse artificial intelligence (AI) tool AlphaFold2 was released in 2021, scientists have used the protein-structure-prediction model to map one of our cells’ biggest machines, discover drugs and chart the universe of every known protein. Despite such successes, John Jumper — … Read more
Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here. Viewers along the eclipse’s path in North America will watch the Moon cross the Sun’s face and block the solar disk, offering the chance to see its outer atmosphere by eye.Credit: Alan Dyer/VW Pics/UIG via Getty … Read more
A diabetes drug related to the latest generation of obesity drugs can slow the development of the symptoms of Parkinson’s disease, a clinical trial suggests1. Participants who took the drug, called lixisenatide, for 12 months showed no worsening of their symptoms — a gain in a condition marked by progressive loss of motor control. Further … Read more
A drug that uses messenger RNA technology has shown early success in addressing the core deficiency behind a rare genetic disorder. The results have ignited hope that the technology — which first gained attention through its breakthrough use in COVID-19 vaccines — could realize its long-awaited promise of generating therapeutic proteins directly in the body. … Read more
Liver tissue from a person with extra fat in the organ.Credit: IKELOS GmbH/Dr. Christopher B. Jackson/Science Photo Library For the first time, the US Food and Drug Administration has approved a drug to treat an obesity-linked liver disease that is on the rise around the globe and is becoming a leading driver of liver failure … Read more
Long-term use of antiretroviral drugs can cause abnormal fat accumulation in people with HIV.Credit: Jose Calvo/SPL People with HIV are the latest group to benefit from the new generation of anti-obesity drugs. If early data about the treatments’ effects are confirmed, the drugs could become key to controlling the metabolic problems often caused by anti-HIV … Read more
People used to discuss simple home remedies that could be used to pass drug tests in the past. This includes the Certo drug test exploit. What is it, and does it work to pass a urine drug test? Consider this a comprehensive guide and answer the questions because it contains all the required information. Related: … Read more