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‘Risk-of-death’ AI save lives in hospital trial

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Jensen Huang, co-founder and chief executive officer of Nvidia Corp., displays the new Blackwell GPU chip, left, and the Hopper GPU chip, right, during the Nvidia GPU Technology Conference (GTC) in San Jose, California.

Nvidia chief executive Jensen Huang shows off the new Blackwell GPU chip (left) at an 18 March event in San Jose, California.Credit: David Paul Morris/Bloomberg via Getty

China’s AI sector could be five to ten years behind the United States, partly because it can’t access the most advanced computer chips. In 2022, the United States imposed export controls on the fastest chips and on equipment that could be used to produce such chips. Even foreign suppliers that produce chips for the US market won’t sell to Chinese developers to avoid falling foul of US sanctions. This has “dramatically limited” China’s progress with training AI models, says computer engineer Yiran Chen.

Nature | 5 min read

In a randomized trial in two Taiwan hospitals, an AI system trained on electrocardiograms reduced deaths among high-risk patients by 31% and deaths by heart problems by more than 90%. “It’s very rare for any medication to [produce] a 31% reduction in mortality, and then even more rare for a non-drug — this is just monitoring people with AI,” says cardiologist Eric Topol. The researchers speculate that the AI predictions increased physicians’ focus on the highest-risk individuals.

New Scientist | 3 min read

Reference: Nature Medicine paper

Almost 40% of made-up text generated by the audio-to-text AI Whisper is harmful or concerning, according to a preprint study that is not yet peer reviewed. While the OpenAI tool only fabricated sections in about 1% of transcripts, these hallucinations often alluded to violence or false personal information. “Doctors are using speech-to-text tools to transcribe patient notes,” says computer scientist and study co-author Allison Koenecke. “If Whisper is making up some transcription that isn’t being said, about how this patient killed someone and they are also taking this medication that is totally made up, imagine how severe those consequences are.”

Science | 5 min read

Reference: arXiv preprint (not peer reviewed)

Image of the week

Songnan Bai, Runze Ding, Song Li, and Bingxuan Pu

This tiny drone on a pogo stick is a Hopcopter. It can bounce up to 1.6 metres high and even do mid-air somersaults. And the hop–flying is remarkably efficient: with a fully charged battery, Hopcopter can move continuously for more than 20 minutes — whereas the same drone without the leg can hover for only a little more than 6 minutes at a time. (IEEE Spectrum | 9 min read)

Reference: Science Robotics paper

Features & opinion

AI and robotics are changing how wildfires are detected and controlled. Drones can provide firefighters with real-time data on how a fire spreads and where the hotspots are — something that currently requires satellite images, which are often many hours old. “Speed is one of the key points. We want to be accurate, but also we want to be very fast in the predictions,” says machine-learning researcher Rossella Arcucci. Her team’s AI systems scour social media for posts about wildfires, which helps to identify an inferno’s starting point. Eventually, AI-controlled water bombers could put out fires autonomously, without putting human firefighters at risk.

The Telegraph | 5 min read

“We shouldn’t fear AI as a technology,” writes media researcher Joseph Jones. “We should instead worry about who owns AI and how its owners wield AI to invade privacy and erode democracy.” Our browsers, apps and smart devices collect huge amounts of information on us. Instead of using this data for everyone’s benefit, it is used to feed machine learning models that suggest ways to ‘nudge’ us towards interacting more with technology and generate even more data, Jones explains. “Under the current business model, the advances of AI and robot technology will enrichen the few while making life more difficult for the many.”

Scientific American | 5 min read

Quote of the day

A quick Google search won’t cut it anymore when it comes to figuring out whether something has been AI-generated or modified, says AI ethics researcher Sandra Wachter. (MIT Technology Review | 22 min read)

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‘Mini liver’ will grow in person’s own lymph node in bold new trial

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A person has received an experimental treatment for the first time that, if successful, will lead them to grow an additional, ‘miniature liver’. The procedure, developed by the biotechnology firm LyGenesis, marks the beginning of a clinical trial designed for people whose livers are failing, but who have not received an organ transplant.

The approach is unusual: researchers injected healthy liver cells from a donor into a lymph node in the upper abdomen of the person with liver failure. The idea is that in several months, the cells will multiply and take over the lymph node to form a structure that can perform the blood-filtering duties of the person’s failing liver.

“It’s a very bold and incredibly innovative idea,” says Valerie Gouon-Evans, a liver-regeneration specialist at Boston University in Massachusetts, who is not involved with the company.

The person who received the treatment, on 25 March, is recovering well from the procedure and was discharged from the clinic, says Michael Hufford, chief executive of LyGenesis, which is based in Pittsburgh, Pennsylvania. But physicians will need to closely monitor them for infection because the person needs to take immunosuppressive drugs so that their body doesn’t reject the donor cells, says Stuart Forbes, a hepatologist at the University of Edinburgh, UK, who is not affiliated with LyGenesis.

Organ crisis

More than 50,000 people in the United States die each year with liver disease. In the end stage of the disease, scar tissue that has accumulated prevents the organ from filtering toxic substances in the blood, and can lead to infection or liver cancer.

A liver transplant can help, but there is a shortage of organs: about 1,000 people in the United States die every year waiting for a transplant. Thousands more aren’t eligible because they are too ill to undergo the procedure.

Gloved hands holding up a fluid bag of the donor liver cells in a lab.

A person received donor liver cells on 25 March that were injected into one of their lymph nodes.Credit: LyGenesis

LyGenesis has been trialling an approach that could help people in this situation — and make use of donated livers that would otherwise go to waste because a person on the transplant waiting list with a compatible health profile hasn’t materialized in time. The company’s strategy delivers the donor cells through a tube in the throat, injecting them into a lymph node near the liver. Lymph nodes, which also filter waste in the body and are an important part of the immune system, are ideal for growing mini livers, Hufford says, because they receive a large supply of blood and there are hundreds of them throughout the body, so if a few are used to generate mini livers, plenty of others can continue to function as lymph nodes.

The treatment has so far worked in mice1, dogs and pigs2. To test the therapy in pigs, researchers restricted blood flow to the animals’ livers, causing the organs to fail, and injected donor cells into lymph nodes. Miniature livers formed within two months and had a cellular architecture resembling a healthy liver. Researchers even found cells that transport bile, a digestive fluid produced by the liver, in the mini livers of the pigs. In this case, they saw no build-up of bile acid, suggesting that the mini organs were processing the fluid.

Hufford says there’s reason to think that the organs won’t grow indefinitely in the lymph nodes. The mini organs rely on chemical distress signals from the failing liver to grow; once the new organs have stabilized blood filtering, they will stop growing because that distress signal disappears, he says. But it’s not yet clear precisely how large the mini-livers will become in humans, he adds.

The company aims to enrol 12 people into the phase II trial by mid-2025 and publish results the following year, Hufford says. The trial, which was approved by US regulators in 2020, will not only measure participant safety, survival time and quality of life post-treatment, but will also help to establish the ideal number of mini livers to stabilize someone’s health. The clinicians running the trial will inject liver cells in up to five of a person’s lymph nodes to determine whether the extra organs can boost the procedure’s success rate.

A stop-gap measure

However, mini livers might not relieve all of the complications of end-stage liver disease, says Forbes, who has formed his own company to tackle liver disease using genetically modified immune cells that stimulate repair. One of the most serious of these is portal hypertension, in which the build-up of scar tissue compresses blood vessels in the liver and can cause internal bleeding.

Hufford acknowledges that the mini livers are not expected to address portal hypertension, but the hope is that they can provide a stopgap until a liver becomes available for transplant, or make people healthy enough to undergo a transplant. “That would be amazing, because these patients currently have no other treatment options,” Gouon-Evans says.

LyGenesis has ambitions beyond mini livers, too. The company is now testing similar approaches to grow kidney and pancreas cells in the lymph nodes of animals, Hufford says.

If the liver trial is successful, Gouon-Evans says, it would be worth investigating whether a person’s own stem cells could be used to generate the cells that seed the lymph nodes. This technique could create personalized cells that capture the diversity of cells in the liver and don’t require immunosuppressive drugs, she says.

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How to watch MGM Plus – subscription plans, free trial, TV and film library

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MGM Plus – the streaming service known as EPIX before Amazon completed its takeover of MGM in 2022 – provides viewers with a wealth of entertainment for a very reasonable fee. 

Given that Metro-Goldwyn-Mayer, the streaming platform’s namesake, has been around for a 100 years now, film buffs and telly addicts get to enjoy an impressive library of hit movies and TV series both old and new.

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Microsoft just gave Copilot Pro a major upgrade – and you can sign up for a free trial now

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Microsoft has announced its Copilot (AI) tools will be rolling out to more users than ever before with the expansion of its Pro tier.

The move will see the more advanced version of the platform available to more users across the globe without the need for confusing subscriptions, with Copilot Pro now available in all 222 countries where Copilot is available.

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How to use Google Gemini Ultra 1.0 (free 2 month trial available)

How to use Google Gemini Ultra

Google has recently made a significant stride in the field of artificial intelligence with the introduction of Gemini Ultra, an AI model that surpasses and now replaces its previous version, Google Bard. This new model is a part of the Gemini suite and is being hailed for its exceptional performance, particularly when compared to OpenAI’s GPT-4, in carrying out complex tasks. Although it’s still early days to see just how good Google Gemini is across all areas.

Google’s latest AI model Google Gemini,  is a significant step forward in AI technology. This system, also known as Gemini Advanced is equipped with the Ultra 1.0 AI model. In a similar way to how Microsoft Copilot is equipped with the GPT-4 AI model. Google Gemini Advanced which utilises the Ultra AI model is now available for users to explore with a two-month free trial, and it comes with an additional 2TB of Google Drive storage.

Gemini Ultra has already been put through rigorous testing, and the results are quite impressive. It’s faster than GPT-4, which is a significant advantage for users who need quick responses. Moreover, it offers unlimited messaging, which is great news for those who use chatbots extensively. However, Gemini Ultra isn’t without its flaws. There are times when it needs more information to complete tasks correctly, which could slow you down a bit.

One of the standout features of Gemini Ultra is its ability to work with Google applications such as YouTube and Google Maps. It can quickly find YouTube videos for you, although it sometimes pulls up videos that are out of date. When it comes to Google Maps, it can give you travel time estimates, but they’re not always accurate, so you might want to double-check them. Google will also soon be making it available in Gmail, Docs, and more.

Using Google Gemini Ultra 1.0

Google explains more about its new Google Gemini Ultra

Gemini Advanced is far more capable at reasoning, following instructions, coding, and creative inspiration. We can’t wait to see what you create. Bard is now Gemini

  • What: Gemini is the best way to get direct access to Google AI. All the collaborative capabilities you know and love are still here, and will keep getting better in the Gemini era. We’ve also evolved the UI to reduce visual distractions, improve legibility, and simplify the navigation.
  • Why: We’re committed to giving everyone direct access to Google AI and, as of this week, every Gemini user across our supported countries and languages has access to Google’s best family of AI models. To better reflect this commitment, we’ve renamed Bard to Gemini.

Try Gemini Advanced to access Google’s most capable AI model, Ultra 1.0

  • What: Gemini Advanced gives you access to our most capable AI model, Ultra 1.0. If you want to be one of the first to access Google’s latest AI advancements as they become available, this is for you. With our Ultra 1.0 model, Gemini Advanced is far more capable at highly complex tasks like coding, logical reasoning, following nuanced instructions, and creative collaboration.
  • Plus, Gemini Advanced will continue to expand with new and exclusive features in the coming months, including expanded multi-modal capabilities, even better coding features, as well as the ability to upload and more deeply analyze files, documents, data, and more. Gemini Advanced is a paid plan available in over 150 countries and territories. It is available and optimized only for English with our Ultra 1.0 model, but can respond to queries in other languages that Gemini is available in.
  • Why: With Gemini Advanced, you can be one of the first to try our most capable AI model, Ultra 1.0. We’re just getting started and Gemini Advanced will continue to get even better. We invite you to join us on this journey. Upgrade to Gemini Advanced.

Chat to supercharge your ideas in the Gemini app

  • What: Get help learning in new ways, writing thank you notes, planning events, and more with Google AI on your phone. Gemini is integrated with Google apps like Gmail, Maps, and YouTube, making it easy to get things done on your phone. You can interact with it through text, voice or images.

    To chat with Gemini on Android, download the Gemini app in the Google Play Store. On iOS, try Gemini in the Google app.

    The Gemini app will be launching on select devices in English in the US. In the coming days, it will be available in Japanese, Korean, and English globally except for the UK, Switzerland, European Economic Area countries, and associated territories. More countries and languages will be coming soon.

  • Why: This is a step towards our vision to deliver the world’s most helpful AI assistant.

Now available in Canada

  • What: You can now collaborate with Gemini on the web in Canada in all supported languagesOpens in a new window, including English and French. The Gemini app is coming soon, starting with English.
  • Why: As we continue to build Gemini responsibly, we’re expanding access to more countries and regions.

When we consider the cost, Gemini Ultra seems to offer a good deal. It comes with a two-month free trial, which gives you plenty of time to decide if it’s right for you. The subscription price is on par with GPT-4, but Gemini Ultra includes some extra benefits like Google One Premium. This could be a deciding factor for those looking for more bang for their buck.

Gemini Ultra also shows potential in more specialized areas like solving complex math problems and analyzing images. While it’s not perfect and does make mistakes from time to time, these features are promising and suggest that with a bit more development, Gemini Ultra could become a very powerful tool.

However, there are some concerns, especially when it comes to educational use. Gemini Ultra has the ability to get around content restrictions, which could be problematic in a classroom setting. Educators should be vigilant and supervise its use to ensure the content remains appropriate and accurate for students.

Here are some other articles you may find of interest on the subject of Google Gemini :

Performance in Understanding and Generating Text

  • Gemini Ultra 1.0:
    • Excels in speed and efficiency.
    • High accuracy in reasoning and creative problem-solving.
    • Demonstrates versatility in technical tasks, such as generating Python code.
  • GPT-4:
    • Offers detailed and nuanced explanations.
    • Engages effectively in complex reasoning tasks.
    • Sophisticated understanding of context and language nuances.

Special Features and Applications

  • Gemini Ultra 1.0:
    • Integration within Google’s ecosystem (Gmail, Docs, Sheets, Slides).
    • Advanced capabilities in both code generation and creative tasks.
    • Part of the Google One AI Premium plan, offering AI tools with cloud storage.
  • GPT-4:
    • Robust in creating interactive experiences, such as text-based games.
    • Capable of producing comprehensive documentation and guides.
    • Flexibility for integration across a wide range of applications via OpenAI’s API.

Usability and Integration

  • Gemini Ultra 1.0:
    • Aimed at users seeking an all-in-one solution combining AI with cloud storage and productivity tools.
    • Offers a premium plan that includes additional storage.
  • GPT-4:
    • Benefits from OpenAI’s API for easier integration across platforms.
    • Suitable for developers and businesses looking to embed AI functionalities.

Limitations and Areas for Improvement

  • Gemini Ultra 1.0:
    • Inconsistencies in interpretation and narrative generation tasks.
    • Initially relied too much on Python code for reasoning, leading to errors.
  • GPT-4:
    • Struggled with incorporating images correctly in PDF generation due to format issues.
    • Demonstrated potential in comprehensive content creation beyond text.

Summary

  • Gemini Ultra 1.0 emphasizes speed, integration with Google’s services, and efficiency, making it a practical choice for users in the Google ecosystem.
  • GPT-4 showcases depth, versatility, and detailed content generation, offering robust functionalities for developers and content creators.
  • The choice between the two depends on user priorities: integration and speed with Gemini Ultra or depth and flexibility with GPT-4.
  • Both models are evolving, promising enhancements in AI-driven applications.

Future updates for Google Gemini

Google isn’t resting on its laurels with Gemini Ultra. They’re planning to roll out improvements, including the integration of Alpha Code 2 and other technologies that could enhance its coding and geometric problem-solving abilities. These updates are definitely something to watch out for, as they could significantly improve what Gemini Ultra can do.

The AI market is heating up, and Gemini Ultra is Google’s way of keeping up with the competition. With researchers branching out into new startups, the race for innovation is fierce. The progress of Gemini Ultra will be an interesting aspect of this dynamic industry.

When we put Gemini Ultra and GPT-4 head-to-head, it’s clear that Gemini Ultra has some unique selling points, like its speed and the unlimited messaging option. However, GPT-4 still outshines it in some areas. Gemini Ultra is catching up, but it hasn’t quite reached the level of GPT-4 in every aspect.

Gemini Ultra is an new AI tool with notable strengths in response time and its pricing structure, but it’s not without areas that need work. As with any technology that’s still developing, whether it’s the right choice for you will depend on your specific needs. It’s worth keeping an eye on the updates that are on the horizon for Gemini Ultra. These improvements could give it the extra capabilities it needs to outdo its rivals in the AI space.

 

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John Lennon Murder Without A Trial premiers on Apple TV Dec 6th

Apple TV debuts trailer for John Lennon Murder Without A Trial

The upcoming Apple TV+ three-part documentary series “John Lennon: Murder Without A Trial” promises to shed new light on one of the most shocking events in music history: the murder of Beatles member John Lennon. The series is scheduled to premiere globally on December 6, and it’s already generating substantial buzz for its exclusive content and in-depth investigation of Lennon’s tragic end.

The Apple TV John Lennon documentary delves into the circumstances surrounding Lennon’s murder and the subsequent conviction of his confessed killer, Mark David Chapman. The docuseries features exclusive eyewitness interviews and previously unseen crime scene photos related to the murder, offering a fresh perspective on a crime that has been extensively covered in the media since it occurred in December 1980.

The series is narrated by Emmy Award winner Kiefer Sutherland, whose distinctive voice adds a layer of gravitas to the proceedings. It includes interviews with key individuals involved in the case, such as Richard Peterson, a taxi driver who witnessed the shooting; Jay Hastings, a doorman at The Dakota building who heard Lennon’s last words; David Suggs, Chapman’s defense lawyer; Elliot Mintz, a confidant to Lennon and Yoko Ono; and Dr. Naomi Goldstein, the psychiatrist who first assessed Chapman. These firsthand accounts provide a comprehensive look at the events leading up to and following Lennon’s untimely death.

Apple TV John Lennon documentary

Here are some other articles you may find of interest on the subject of Apple TV+:

The production team behind “John Lennon: Murder Without A Trial” is no stranger to tackling complex and challenging subjects. The series is produced by the BAFTA and Emmy Award-winning team at 72 Films, directed by Nick Holt and Rob Coldstream, with executive producers David Glover, Mark Raphael, and Coldstream, alongside producers Simon Bunney and Louis Lee Ray. Their combined experience and expertise in documentary filmmaking lend credibility to the series, ensuring a thoughtful and thorough exploration of Lennon’s murder.

One of the standout aspects of  Apple TV John Lennon documentary  is the depth of its research. The production team was granted extensive Freedom of Information Act requests from the New York City Police Department, the Board of Parole, and the District Attorney’s office. This unprecedented access to official documents and records has allowed the series to delve into the intricacies of the case in a way that few previous documentaries have been able to do.

John Lennon: Murder Without A Trial promises to be a compelling watch not just for fans of Lennon and The Beatles, but also for anyone interested in true crime or historical documentaries. Its release on Apple TV+ on December 6 is sure to be marked by anticipation and intrigue as viewers prepare to gain new insight into a case that has captivated the world for over four decades.

With its exclusive interviews, unseen crime scene photos, and deeply researched content, the series promises to provide a fresh and comprehensive look at a case that continues to fascinate and horrify in equal measure.

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