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Bisnis Industri

El Real Madrid llora por Dani Carvajal: el defensa tiene un triple break

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mia verdadero madrid Este domingo oficializó lo que ya era evidente. Dani Carvajal Sufre una grave lesión del ligamento cruzado. “Se ha confirmado que tengo una lesión grave del ligamento cruzado y tendré que pasar por el quirófano y estar de baja unos meses”.Así lo afirmó el propio futbolista la noche del sábado en las redes sociales. La enfermedad ha sido confirmada ahora por el Club Blanco a través de un comunicado.

“Un desgarro del ligamento cruzado anterior, un desgarro del ligamento colateral externo y un desgarro del tendón poplíteo en la pierna derecha. Será operado en los próximos días”.“, dice el escrito.

Eso sí, el futbolista ya ha mostrado en sus redes sociales su intención de volver más fuerte tras esta repentina lesión que le podría provocar verdadero madrid Busque soluciones en el mercado. “Ya tengo muchas ganas de empezar mi recuperación y volver como una bestia. Muchas gracias a todos por vuestros mensajes, me siento muy querido”.“Karva”, dijo en su publicación.

El Real Madrid llora por Dani Carvajal: el defensa tiene un triple break

mal gesto

Desmayo por carvajal Llegué cuando el partido contra el Villarreal del sábado en el Santiago Bernabéu (2-0) agonizaba. El defensor fue a defender la jugada en contra. Jérémy Pineau Cuando intentó golpear la pelota con la pierna derecha, hizo una mala jugada y se quedó atascado. Una fea jugada lo dejó en el suelo. Más tarde, cuando intentó caminar, rápidamente se dio cuenta de que no tenía estabilidad en la rodilla y tuvo que ser transportado en camilla con lágrimas en los ojos.

El Real Madrid llora por Dani Carvajal: el defensa tiene un triple break

El jugador blanco y sus compañeros se vieron muy afectados por esta importante lesión que dejó al club madrileño en una situación complicada en defensa.

El Real Madrid llora por Dani Carvajal: el defensa tiene un triple break

Es más, aquellos Anceloti Saben lo que es sufrir una lesión grave en el trasero. Cortesía, militar y elogios. Realmente han caído últimamente. Ahora le toca carvajal, Debería estar varios meses fuera de acción.

Muchos mensajes de apoyo.

carvajal No ha dejado de recibir mensajes de apoyo en las últimas horas. Una de las palabras más sentidas vino de un familiar y excompañero Joselu Matto. “Escribo entre lágrimas y siento que desearía que me pasara esto. Ahora nos queda un camino que sé que seguirás admirablemente, como todo lo que haces. Te amo hermano, siempre contigo”, escribió el delantero. redes sociales.



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Business Industry

El drama criminal de Fox de la década de 2000, Prison Break, está prosperando en la cima de las listas de Netflix

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Si miras algunos programas desde una perspectiva mesurada, te darás cuenta de que no son tan buenos como recuerdas. Sin embargo, en algunos casos, este cambio en la calidad percibida –moldeado por la retrospectiva y la nostalgia– no es importante, siempre y cuando el programa tenga como objetivo entretener. Por ejemplo, “Prison Break” comienza con una premisa sólida.en el que la inminente sentencia de muerte de un hombre inocente desencadena un elaborado plan de fuga liderado por su hermano, presentando apuestas dramáticas apropiadas dentro de un arco narrativo definido. Sin embargo, el entretenimiento del programa disminuye después de la tercera temporada, ya que su trama depende de desarrollos sorprendentemente intrincados que comienzan a parecer confusos en todos los sentidos equivocados. Sin embargo, a pesar de lo grandiosas que fueron las dos primeras temporadas, “Prison Break” todavía se recuerda con cariño, y su impacto cultural está determinado solo por esos impresionantes episodios iniciales.

Parece que la buena voluntad del programa todavía está funcionando a su favor, ya que “Prison Break” ya aterrizó en Netflix. mundial Los 10 mejores programas de televisión, cuyas primeras tres temporadas ocuparon el cuarto, quinto y sexto lugar, respectivamente (vía Todom). Esta triple ganancia parece un poco aleatoria al principio, pero el algoritmo de Netflix tiende a funcionar de maneras misteriosas, impulsando programas/películas antiguas en ciertos puntos o provocando sin darse cuenta que una joya olvidada sea reevaluada. “Prison Break” es sin duda uno de los mejores programas que resurge en el ranking de la plataforma de streaming, con la mayor cantidad de horas netas de visualización para la primera temporada: ¡54.100.000!

Claro, “Jail Break” está empezando a perder relevancia después de que sus héroes, bueno, Salir de prisiónpero echemos un vistazo a lo que hace que este programa sea tan querido y los mejores aspectos a tener en cuenta si planeas ver las primeras tres temporadas en Netflix.

La premisa original de Prison Break ayuda a llevar a cabo todo el espectáculo.

Spoilers Para seguir “Jail Break”.

“Jailbreak” comienza con la separación de dos hermanos, Lincoln Burroughs (Dominic Purcell) y Michael Scofield (Wentworth Miller), después de que Lincoln sea acusado injustamente de matar al hermano del vicepresidente. Debido a la naturaleza de alto perfil del caso, Lincoln fue rápidamente sentenciado a muerte y encarcelado en la prisión estatal de Fox River, por lo que Michael cometió deliberadamente un robo a mano armada para ser sentenciado a la misma prisión. Por supuesto, escapar de Fox River no es una broma, ya que no le deja a Michael otra opción que manipular las probabilidades a su favor con el tiempo, lo que lleva a alianzas y rivalidades que afectan el resultado de la eventual fuga de la prisión. El significado de la revelación de los tatuajes de Michael todavía se considera uno de los puntos culminantes del programa, ya que cada parte de su piel tatuada significa algo y contiene una clave para el futuro que él y Lincoln quieren disfrutar juntos.

La naturaleza de suspenso de la serie continuó durante las dos primeras temporadas y, en el momento de su emisión, ninguna otra serie había explorado una idea tan única, lo que ayudó a que “Prison Break” se destacara. Otro programa popular en Fox. Cada vez que la serie revela los verdaderos motivos de un recluso o un querido amigo o nos da un vistazo al plan maestro de Michael que se basa en su conocimiento de arquitectura para burlar a las autoridades, “Prison Break” brilla. realmente brillante. Sin embargo, a medida que pasan las temporadas, lo que alguna vez fue genial comienza a parecer aburrido, ya que los elementos más tontos no combinan bien con el tono engreído y la naturaleza exagerada de algunas de las actuaciones contribuyen a una experiencia que, en el mejor de los casos, se siente muy mediocre. . Pero bueno, al final del día, lo único que recordarás es la diversión que pasaste viendo a Michael y sus amigos. Navega por tramas complejas para hacer lo que mejor saben hacer: sobrevivir.

“Prison Break” se está transmitiendo actualmente en Netflix.


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Politics

Después de 16 años, todavía estoy enojado porque Prison Break le hizo esto a mi personaje favorito.

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resumen

  • La historia de Mahoney en la temporada 4 de Prison Break involucra la muerte innecesaria de su hijo.
  • Matar a Cameron fue un flaco favor para el personaje de Mahoney y solo sirvió para darle un propósito en la historia.
  • La temporada 4 tuvo muchos problemas, incluido no saber qué hacer con Mahoney y la mayoría de los personajes después de su fuga de Sona.

fuga de la prisión La cuarta temporada se emitió hace 16 años y todavía estoy decepcionado por la forma en que trataron a Alex Mahoney. Después de una primera temporada casi perfecta, fuga de la prisión La segunda temporada de la serie tenía la difícil tarea de cómo continuar la serie ahora que la “fuga de prisión” había terminado. Pero el siguiente capítulo de la serie no fue demasiado sorprendente. Michael y los demás ahora estaban huyendo y, en lugar de escapar de la prisión, su objetivo era evitar ser capturados nuevamente. Para aumentar las apuestas, fuga de la prisión La temporada 2 nos dio a Alex Mahoneyque es un agente del FBI muy inteligente.

Mahone era peligrosamente bueno en su trabajo, aunque la verdadera razón por la que estaba tan ansioso por atrapar a Michael Scofield y sus asociados no se reveló hasta más adelante en la temporada. fuga de la prisión La temporada 2 no fue tan buena como la temporada 1, ya que disfruté siguiendo a Michael y los demás mientras escapaban mientras Mahone los perseguía. Esto sólo funcionó porque Mahone era un gran villano de la televisión que podía robarse el programa cada vez que aparecía en la pantalla. Desafortunadamente, mientras… Mahone se salvó a medida que avanzaba el espectáculo.La cuarta temporada casi arruinó la historia del personaje.

Relacionado

Reinicio de Prison Break: confirmación y todo lo que sabemos

La exitosa serie “Prison Break” se emitió en Fox durante cinco temporadas y ahora, según se informa, se está desarrollando una nueva versión del popular drama para el gigante del streaming Hulu.

Prison Break Temporada 4 El hijo de Mahoney fue brutalmente asesinado

La muerte de Cameron Mahoney en la fuga de prisión fue injustificada

Mahoney en la cuarta temporada de Prison Break

La fuerza impulsora detrás de la historia de Mahoney fuga de la prisión Su hijo era Cameron. Después de casi arruinar su carrera, Alex Mahoney acepta un trabajo en la empresa siempre que pueda mantener a su familia a salvo. Sin embargo, al comienzo de la temporada 4, Wyatt Mathewson mata al hijo de Mahoney por orden del general Krantz. La misión de Mathewson es cazar a Michael, Lincoln y Sarah, y no hará nada para cumplirla. Ahora que Alex es socio de Michael desde hace más de un año, El asesino fue a la casa de Mahoney, amenazó a su esposa y mató a su hijo.

hecho de que
fuga de la prisión
Sin saber realmente qué hacer con Mahoney después de su fuga, Sona es uno de los muchos problemas de la cuarta temporada.

El problema de que Mathewson haya matado al hijo de Mahoney es que es una tragedia. fuga de la prisión Este momento sólo tuvo valor de shock. Después de pasar mucho tiempo con Mahoney y desarrollarlo como personaje, fuga de la prisión Se arriesgó a tirar todo por la borda sólo para tener una razón para seguir trabajando con Michael contra Krantz. Mahoney estaba reparando la relación con su familia y estaba a punto de regresar a casa cuando ocurrió el asesinato de su hijo. Me sentí como… Matar a Cameron fue un insulto al carácter de Mahoney Sólo sirvió para darle un propósito.

La historia de Mahoney fue uno de los muchos problemas de la temporada 4 de Prison Break

La temporada 4 de Prison Break fue probablemente la peor de la historia

hecho de que fuga de la prisión Sin saber realmente qué hacer con Mahoney después de su fuga, Sona es uno de los muchos problemas de la cuarta temporada. Después de seguir a los personajes mientras escapan y luego a una nueva prisión, fuga de la prisión Se me acabaron las ideas. Ahora la dinámica había cambiado y los personajes estaban trabajando con una agencia gubernamental para llevar a cabo un atraco. La misión de venganza de Mahoney no fue tan interesante como podría haber sido, y todo lo relacionado con la tarjeta de datos conocida como Skyla parecía demasiado genérico y aburrido para un programa convincente como fuga de la prisión Fue una vez.

Póster de la serie Prison Break
fuga de la prisión

3.5

Prison Break trata sobre dos hermanos que intentan descubrir una conspiración política mientras escapan de uno de los lugares más seguros de la Tierra. Cuando el delincuente de poca monta Lincoln Burrows (Dominic Purcell) es condenado injustamente por asesinar al hermano del vicepresidente, su hermano Michael Scofield (Wentworth Miller) es encerrado para organizar una audaz fuga de la prisión utilizando los planos de la instalación tatuados en su cuerpo.

el calumnia
Curtis Lom, Sarah Wayne Callies, Marina Benedict, Amin El Gamal, Wentworth Miller, Steve Mouzakis, Dominic Purcell, Bobby Naderi, Christian Michael Cooper
fecha de lanzamiento
29 de agosto de 2005
Estaciones
5
red
el zorro

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Entertainment

A big-screen iPad that doesn’t break the bank

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Compared to the iPad Pro, the changes Apple made to the iPad Air are more modest. Rather than a total redesign, the iPad Air is getting some expected and slightly overdue changes: a new screen size, a new processor and a front-facing camera that is placed on the landscape side of the tablet.

Yes, that’s some faint praise, but there’s a lot to like about the new iPad Air. It’s long been the best overall iPad, straddling the line between the budget entry model and the wildly powerful and expensive Pro lineup. That’s the case here, again. But now that the 13-inch iPad Pro is even more pricey than before, it’s good to see a large-screen iPad that doesn’t cost well over $1,000.

The 11-inch iPad Air is identical in size and weight to the old one, though the screen is .1 inches bigger this time. So there’s not a whole lot to say about that one. The 13-inch Air, however, feels quite a bit like the old 12.9-inch iPad Pro that was just replaced today. Indeed, it’s identical in all dimensions, but a little bit lighter (1.36 pounds instead of 1.5).

iPad Air M2 2024iPad Air M2 2024

Photo by Nathan Ingraham / Engadget

That makes it a little more approachable as a hand-held tablet, though I still feel like an iPad this large is best suited to either be used in a keyboard dock or flat on a table with an Apple Pencil. That said, Apple says that about half of iPad Pro sales were for the larger model, so there’s clearly an appetite for this bigger screen. There’s definitely something luxurious about using such a large screen tablet, provided it’s easy to handle, and that’s the case with the iPad Air (at least in the limited time I’ve had so far to handle the device).

I also got to try the new Apple Pencil Pro, which is compatible with the new Air. As I said here, the new tricks like barrel roll for changing the shape of your brush and a squeeze feature to bring up tools like a brush picker are solid additions, and I’m glad that Apple didn’t increase the Pencil’s price given these new features.

iPad Air M2 2024iPad Air M2 2024

Photo by Nathan Ingraham / Engadget

These tablets might not have the wow factor that I experienced when checking out the iPad Pro, but that’s OK. From my first look, it feels like the iPad Air lineup offers most of the same experience that you’ll get with an iPad Pro — at least in ways that normal buyers will recognize. And I think Apple did well on pricing this time out. The 11-inch iPad Air costs $599, same as before, but it now has a more reasonable 128GB of storage. The 13-inch model is priced at $799, an expected price bump for the larger screen. It’s the first time you can get a large-screen iPad for less than a grand, and I’m definitely curious to see if that helps to improve iPad sales.

You can read my first impressions of the new iPad Pro M4 right here.

Follow all of the news live from Apple’s ‘Let Loose’ event right here.

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Finally! After a 7-year wait, this monitor could well be the best pro-level 8K display ever — will Asus be able to break the curse of failed 8K monitor launches with the PA32KCX Mini LED pro screen?

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Mini LEDs are typically found in gaming monitors. Unlike LCD backlights, they offer a broad contrast range, with deeper, near-OLED quality levels of black, that enrich and enhance the dynamism of both SDR and HDR content.

Asus has brought Mini LED technology to the ultra-high-end business monitor market for the first time with its new 32-inch ProArt Display PA32KCX. The 8K screen (that’s a whopping 7,680 x 4,320 pixels – 275 PPI), is aimed at professional photographers, video editors and graphics artists.

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Galaxy AI: Break language barriers with One UI 6.1 Live Translate and Interpreter

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With the Galaxy S24, Samsung introduced Galaxy AI, a suite of AI-powered features useful in everyday tasks. Some of its features allow you to converse freely with people who don’t speak your language. It is handy when traveling outside your country or having international meetings.

This article will explain how you can use Galaxy AI’s Interpreter and Live Translate features to break language barriers and communicate without major issues.

How to use Interpreter and Live Translate on Galaxy phones

You can watch our in-depth video below to see how the Interpreter Mode and Live Translate features work on Galaxy phones running One UI 6.1.

However, not all languages are supported in these modes. Supported languages include Chinese, English (India, US, UK), French, German, Hindi, Italian, Japanese, Korean, Polish, Portuguese (Brazil), Spanish (Mexico, Spain, US), Thai, and Vietnamese.

Use Interpreter mode when talking to someone face-to-face who doesn’t understand your language

When you’re talking to someone face to face, and the other person doesn’t understand your language, you should use the Interpreter Mode on your Galaxy device. Here is how you can use it:

1. Swipe down from the top of the screen on your Galaxy phone. Now, swipe down again to reveal the full Quick Panel screen.

2. Now, find the Interpreter Mode toggle and click on it.

3. The Interpreter Mode will open in full-screen mode. Select your language by tapping the language drop-down menu beside the microphone icon. Now, select the other person’s language by tapping the drop-down menu beside the microphone icon at the top. You can tap the button on the left side of the three-dot menu at the top of the screen to make the phone’s UI face the other person.

4. You can now start talking with the other person, and the voices will be transcribed and translated in real time. You can view the recorded and translated text on the phone’s screen.

This is great when you travel to a different country or city where people don’t speak your language.

Use Live Translate during voice calls

You can use the Live Translate feature to talk on a voice call to someone who doesn’t speak your language. To use it, follow the steps listed below.

1. Open the Phone app on your Galaxy device. Tap the three-dot menu on the top-right part of the screen.

2. Click on Live Translate and turn on the toggle.

3. Scroll down, tap on Language in the Me section, and select your language. In this section, you must choose the language that best suits your preferences. In the Voice section, you can choose the voice option and the speed of the speech using the Speech Rate slider. You can enable the Mute My Voice option if you want the other person to hear your translated voice only.

4. Now, scroll down further. In the Other Person section, select the language of the other person. In the Voice section, you can choose the voice option and the speed of the speech using the Speech Rate slider. You can enable the Mute Other Person’s Voice option if you only want to hear the other person’s voice translated into your language.

5. You can even find the option to select a language for each person in your contact list.

Once you are done, you can make or receive calls from people who don’t speak your language. You can see live-translated text on your phone’s screen during the call.

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Gut bacteria can break down artery-clogging cholesterol

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Hello Nature readers, would you like to get this Briefing in your inbox free every day? Sign up here.

Illustration of a lipid nanoparticle mRNA vaccine, a type of vaccine used against COVID-19 and influenza.

A new drug consists of pieces of mRNA encased in a fatty envelope (artist’s impression).Credit: Kateryna Kon/SPL

A therapy that extends mRNA technology beyond vaccines has shown early success in treating a rare genetic disease, propionic acidaemia, that prevents people from processing certain nutrients. The treatment — made by US pharma company Moderna, and known as mRNA-3927 — gives those treated a working copy of the instructions needed to make an enzyme that is missing in people with the disease. In a small clinical trial, half of the participants receiving the therapy saw their risk of life-threatening episodes decrease by 70–80%. But the drug also produced side effects and required frequent infusions.

Nature | 5 min read

Taiwan has been hit with the biggest earthquake the island has seen in 25 years. The magnitude-7.4 quake killed several people, flattened buildings and triggered landslides. But it could have been much worse: in the past two decades, Taiwan has ramped up its efforts to prepare for quakes. It has an early warning system that sends alerts seconds after an earthquake strikes, and many buildings have been upgraded. Taiwan is situated in one of the most seismically active regions in the world and a magnitude-7.6 tremor in 1999 resulted in more than 2,400 deaths.

Nature | 3 min read

A fertility treatment that has been used for 45 years is back in Alabama after being halted in February by the state’s Supreme Court. The court ruled that embryos created using in vitro fertilization (IVF) have the same rights as children, but a new state law in Alabama that protects clinics from legal fallout has allowed IVF treatments to resume. US clinicians and scientists who are working with human embryos are not totally reassured and fear that they will face an increasing number of legal and constitutional challenges. “From a researcher’s perspective, there’s reason to be worried,” says Hank Greely, director of the Center for Law and the Biosciences at Stanford University.

Nature | 5 min read

Researchers have identified gut bacteria that can transform artery-clogging cholesterol into a more harmless form. In previous work, the authors showed that a bacterial enzyme called ismA can metabolize cholesterol into coprostanol, a lipid that is excreted instead of absorbed by the body. They have now identified gut bacteria, including several Oscillibacter species, that correlate with lower cholesterol levels in people. These species could also metabolize cholesterol in lab experiments. Whether these bacteria can directly influence blood cholesterol in people needs to be confirmed, but if they could be delivered to the right place in the gut, it might lead to new treatments.

Nature | 4 min read

Reference: Cell paper

Infographic of the week

‘CROWN’ JEWELS. Graphic labelling features of the Sun's corona.

Source: Nature adaptation from image provided by Nicolas Lefaudeux

Features & opinion

Heart disease, depression, dementia and even early death have all been linked to loneliness. According to a 2023 poll, around one-quarter of adults worldwide feel very or fairly lonely, with twice as many young people reporting loneliness as the elderly. Early results from neuroscience suggest that loneliness might alter aspects of the brain, such as the connections between neurons and the volume of grey matter. Links are also emerging between loneliness and how the brain processes feelings of stress, motivation or reward.

Nature | 11 min read

LONELINESS AND HEALTH. Graphic shows lonely adults are more likely to be diagnosed with a range of physical health issues.

Source: The Cigna Group

Public-health researcher Kelly Cobey wants the research community to move away from narrow assessment metrics such as papers in high-impact journals. As co-chair of the Declaration On Research Assessment, Cobey firmly believes in using ‘narrative’ CVs for job applications, promotions and funding, and yet she struggles to write one herself. “Researchers need explicit evaluation criteria that help them to write narratives by spelling out how different aspects of the text will be weighted and judged,” writes Cobey. And reform can’t be done on the cheap: it needs investment from the top and input from the research community. An iterative approach will ensure that the new systems are better than those they are replacing.

Nature | 5 min read

“Astrophysics is an exercise in incredible experiments not runnable on Earth,” says theoretical physicist Avery Broderick. “And black holes are an ideal laboratory.” What makes black holes appealing to physicists is their extreme simplicity: an extraordinary amount of mass in a ridiculously small space. Black holes also challenge physicists’ ideas about general relativity and quantum mechanics. Astronomers can observe the gravitational waves emitted by colliding black holes, and maybe understand how they deviate from Einstein’s theories.

The New Yorker | 12 min read

Quote of the day

The loss of pristine tropical forests slowed last year, but ten football pitches’ worth of forest were still lost every minute in 2023, found an analysis by environmental scientist Mikaela Weisse and her colleagues at the environmental think tank World Resources Institute. (Nature | 3 min read)

Reference: Global Forest Watch map

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Gut bacteria break down cholesterol — hinting at probiotic treatments

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Scientists have pinpointed human gut bacteria that have a useful tool: an enzyme that can convert artery-clogging cholesterol into a more harmless form that is not absorbed by the body. The finding points towards possible treatments for high cholesterol levels.

Although the newly described bacterial species can metabolize cholesterol in the laboratory, whether they can cause changes in their hosts’ blood cholesterol levels has yet to be confirmed in animal models or clinical trials.

“It’s very exciting to further explore,” says bioinformatician Daoming Wang at the University of Groningen in the Netherlands, who was not involved in the research.

Wang adds that the methods in the study, published on 2 April in Cell1, address thorny challenges in human microbiome research. The research is “really outstanding”, agrees bioinformatician Alexander Kurilshikov at the University of Groningen, who also was not involved in the work.

Missing link

It has been established that the human gut microbiome affects cholesterol levels, and previous research has pointed to microbial enzymes that might be involved. A 2020 study2 identified a bacterial enzyme called ismA that can convert cholesterol into coprostanol, a lipid that is excreted instead of absorbed by the body. People whose gut bacteria made this enzyme had lower cholesterol levels in their blood than did those who did not. This study was published by the same research group — led by gastroenterologist and microbiologist Ramnik Xavier at the Massachusetts General Hospital in Boston — that is responsible for the new finding. Until now, it was not clear which bacteria produced enzymes that metabolize cholesterol.

For the current study, the researchers analysed microbial genomes in stool samples from 1,429 participants in a long-term study of risk factors for cardiovascular disease. The team found many gut-bacteria species, including those in the genus Oscillibacter, that were correlated with lower cholesterol levels. The researchers confirmed their results in participants in two independent studies.

Dark matter of the gut

Next, the team searched two Oscillibacter species and one other bacterial species for genes similar to those known to affect cholesterol metabolism. To do so, the scientists used a deep-learning algorithm that they call a ‘protein language model’. The model assesses not only the features of a gene itself, but also predictions of how the protein encoded by the gene will fold into a 3D structure. The extra information makes the algorithm more sensitive than those that rely on only information about the gene.

They found that the three species have genes encoding proteins that are structurally similar to ismA and other enzymes involved in cholesterol metabolism.

This technique is “innovative and significant”, says Wang, because it provides a method for getting at the ‘dark matter’ of the microbiome: the large number of bacterial genes that aren’t similar enough to any known genes to give clues about their function.

The authors also showed in lab experiments that these three species can metabolize cholesterol. Xavier suspects, on the basis of their data, that there are “many more” Oscillibacter species to be discovered than the 25 identified in the study.

Treatment barriers

If the bacterial species or enzymes could be delivered to the right place in the gut, it might be possible to lower the necessary dose of drugs such as statins to reduce or manage cholesterol levels.

But there are hurdles facing development of such a treatment. Delivering beneficial bacteria has worked very well in treating infections with the common pathogen Clostridium difficile, says Xavier, but C. difficile’s toxin kills off a lot of bacteria, creating space for helpful bacteria. Individuals receiving treatment for high cholesterol would still have their usual gut microbiome community, he says, which could squeeze out the beneficial bacteria.

“It’s a long way off,” says Xavier. But “maybe in patients at risk, we could lower that risk at a much earlier stage”, he says.

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How AI could make or break your career

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These are already turbulent times for employees in the technology sector. Depressingly we’ve seen a fall in advertised vacancies and several mass layoffs initiated by both major companies and smaller startups. Yet, on the plus side we’ve also witnessed inflation-busting salary rises tough to fill positions.

Now, in its predictions for 2024, the research and advisory firm Forrester has warned that heavy use of AI tools in recruitment will lead to further “misconnections, mischief and mayhem”. It believes at least one well-known company will hire a candidate who doesn’t actually exist and at least one business will employ a real candidate for a non-existent job.

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iOS 18 might break the iPhone’s iconic app grid, and it’s a change no one asked for

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The iPhone and iOS are not messy. Throughout their nearly 20-year life they’ve embodied precision and consistency, with no design element left to chance. There’s never a detail unexplained or unaccounted for; and one thing you absolutely will not find, on either the phone itself or in its operating system, is wasted space.

This is why I’m concerned that iOS 18 might introduce, for lack of a better word, intentional sloppiness.

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