Doctors Combined a Heart Pump and Pig Kidney Transplant in Breakthrough Surgery

Doctors Combined a Heart Pump and Pig Kidney Transplant in Breakthrough Surgery

The kidney used in the latest NYU transplant was procured from a pig with a single genetic edit—the removal of a gene that produces a sugar known as alpha gal. This sugar appears on the surface of pig cells and seems to be responsible for rapid rejection in humans. The pig was engineered by Revivicor, … Read more

He Got a Pig Kidney Transplant. Now Doctors Need to Keep It Working

He Got a Pig Kidney Transplant. Now Doctors Need to Keep It Working

Other than rejection of the organ, one of the most common transplant complications is infection. Doctors have to strike a balance when prescribing immunosuppressive drugs: too low a dose can lead to rejection, while too much can make a patient vulnerable to infection. Immunosuppressants are powerful drugs that can cause a range of side effects, … Read more

Time to sound the alarm about the hidden epidemic of kidney disease

Time to sound the alarm about the hidden epidemic of kidney disease

Kidney disease is growing worldwide. The secretariat of the World Health Organization has welcomed the call to include it as a non-communicable disease that causes premature deaths.Credit: Vsevolod Zviryk/SPL A quiet epidemic is building around the world. It is the third-fastest-growing cause of death globally. By 2040, it is expected to become the fifth-highest cause … Read more