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Pregnancy advances your ‘biological’ age — but giving birth turns it back

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A young woman holds her newborn baby in a hospital bed at at the University of Chicago Medical Center.

Giving birth shifts a person’s DNA markings back toward a more youthful state, but this trend is less noticeable in new birth parents with obesity.Credit: Chicago Tribune/Getty

Aches and pains aren’t all that pregnancy shares with ageing. Brewing a baby leads to changes in the distribution of certain chemical markers on a pregnant person’s DNA — changes similar to those that are a hallmark of getting older. But new research shows that, several months after a person gives birth, the chemical patterns revert to an earlier state1. The results strengthen previous work in mice and preliminary results in humans2.

It’s not surprising that pregnancy takes a toll, but the reversal was “somewhat unexpected”, says perinatal-health specialist Kieran O’Donnell at Yale University in New Haven, Connecticut, a co-author of the study. It was published 22 March in Cell Metabolism.

Aged DNA

The chemical tags analysed in the study are called methyl groups, and they are added to DNA in a process called methylation. They are one example of the ‘epigenome’, features of DNA that change gene activity without altering the genetic code.

DNA-methylation patterns can be used to estimate a person’s ‘biological age’, which reflects the physiological stresses that a person’s body has accrued over time. Some research has found that biological age is a better predictor of health problems such as cardiovascular disease3 and dementia4 than a person’s chronological age.

But unlike chronological age, “biological age is quite flexible; it’s a fluid parameter. It can go up and down”, says biomedical scientist Vadim Gladyshev at Harvard Medical School in Boston, Massachusetts. Last year, his team published a study in Cell Metabolism2 that noted a decrease in biological age after pregnancy in mice and suggested that there could be a similar effect in humans. Cessation of several other stressful conditions also reversed biological age.

Obesity’s effect

The new study confirmed Gladyshev and colleagues’ results in humans and also showed that not everyone bounces back from pregnancy to the same degree. People who were at the cusp of obesity before pregnancy shed fewer years of biological age in the three months after birth than did people who had a body weight classified as “normal,” O’Donnell and his colleagues found. Meanwhile, people who breastfed exclusively experienced a greater reduction in biological age than did those who used formula or a mix of formula and breast milk.

Some participants’ biological ages were a few years younger postpartum than in early pregnancy. That’s “one thing that caught my eye”, says ageing-biologist Yousin Suh at Columbia University in New York City, who was not involved in the work.

The researchers didn’t measure the biological age of participants before pregnancy, so “we can’t claim that this is a rejuvenation effect”, O’Donnell says. But the data are suggestive, and he’d like to follow up with the participants in the future.

Not to worry

Interpreting Gladyshev and O’Donnell’s findings is tricky, some researchers say. Methylation clearly changes during pregnancy, but “we would be wrong to assume pregnancy is a state of accelerated ageing”, says Dena Dubal, a physician-scientist and specialist in ageing at the University of California, San Francisco. Dubal thinks that methylation might not be a hallmark of ageing but could instead underlie some of the sweeping changes that the body must undergo to support a growing fetus, such as altered gene expression.

Suh isn’t so sure. “Methylation is, thus far, one of the most robust markers of biological age,” she says.

Whether a reversible state can truly be called “age” is “a really important point”, O’Donnell says. “Perhaps as we begin to focus on pregnancy as a new area for ageing research, maybe there’s new terms and terminology that will need to be developed.”

In the end, people shouldn’t worry about any pregnancy-related increase in their biological age, scientists say. “We are talking about, you know, changes of about two, three years,” Gladyshev says.

And Dubal points out that pregnancy should not be conceptualized as a biological problem, even for people who don’t maximize recovery by breastfeeding. “While the benefits of breast feeding are many, its absence is not a dangerous predicament,” she says.

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It’s time to enhance age assurance and content moderation to protect children

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In today’s digital-first environment children are being routinely exposed to harmful, age-restricted and even illegal content online. The continued proliferation of smart devices and easy, anywhere access to user-generated content (UGC) through social media and chat platforms is only exacerbating the issue.

At the tap of a button, individuals can now be exposed to more adult, extreme and illegal content than ever before. And in the UK it has been revealed that children themselves are now the biggest perpetrators of sexual abuse against children (52%).

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Fortifying the Future: Mastering Cybersecurity in the Age of Generative AI

Mastering Cybersecurity in the age of Generative AI

In an era where digital transformation is at the heart of business evolution, Generative AI stands out as a marvel of innovation. This subset of artificial intelligence, known for its ability to create original content—from text to images—holds immense potential. However, its capabilities also make it a double-edged sword in the realm of cybersecurity. For businesses leveraging this powerful technology, the need for a robust security framework is non-negotiable. This article delves into the methods and strategies to secure AI business models against the burgeoning threats in cyberspace.

Securing Data for AI Models

At the core of generative AI’s power is data—vast quantities of it. The integrity and security of this data are paramount. It begins with data discovery and classification, a meticulous process that sorts through the digital deluge to identify sensitive information and safeguard it appropriately. Cryptography then comes into play, transforming this data into a cipher that is impenetrable without the correct keys, effectively nullifying data breaches.

In tandem with these measures, access controls are indispensable. With techniques like Multifactor Authentication (MFA), the security net tightens, ensuring that only those with verified credentials can reach the sensitive nucleus of AI models.

How to protect your AI Models

Once the data is locked down, attention shifts to the AI models themselves. These models are the engines of generative AI, and like any engine, they can be tampered with or corrupted. Routine scans for malicious Cybersecurity code, fortifying systems against cyber attacks, and role-based access control are critical defense strategies. Moreover, the pedigree of the data sources feeding into these models must be scrutinized for trustworthiness and legality, with APIs serving as secure conduits for data flow and interaction.

Other articles you may find of interest on the subject of Generative AI :

Deploying generative AI is not a set-and-forget affair. It demands continuous vigilance from Cybersecurity threats. Monitoring the inputs that feed the AI is crucial to prevent the propagation of misinformation or malicious content. Semantic guardrails can curtail the misuse of AI-generated content, while machine learning tools adeptly detect and respond to anomalies and threats.

Supporting these efforts are SIEM systems, which act as the watchtowers of cybersecurity, providing real-time alerts and insights. Complementing SIEM, SOAR solutions automate the responses to low-level security events, ensuring rapid containment and resolution.

AI Cybersecurity

The IT infrastructure is the backbone that supports the lofty ambitions of generative AI. It must embody the CIA Triad—confidentiality, integrity, and availability. Each component of the infrastructure, from the humblest server to the most complex network, must be treated as a potential vulnerability and fortified accordingly.

No AI system operates in a vacuum. Governance and compliance are the ethical compass and legal scaffolding that ensure AI operates within the boundaries of moral and legal acceptability. Establishing governance frameworks that dictate how AI should be used and ensuring compliance with ever-evolving regulatory landscapes are as vital as any technical safeguard.

In summary, the security of generative AI is a multi-faceted challenge that extends from the granular level of data protection to the broader strokes of governance and compliance. It requires a harmonious blend of advanced technologies, stringent policies, and continuous monitoring. The key to harnessing the full potential of generative AI lies in constructing a security architecture that is as dynamic and intelligent as the AI it seeks to protect.

Businesses must recognize that securing generative AI is not a hurdle but an enabler of innovation. In doing so, they not only defend against the specters of cyber threats but also build the trust and reliability that are the currency of the digital economy. With the right security framework, the promise of generative AI can be fully realized, propelling businesses towards a future where creativity and cybersecurity go hand in hand.

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Willie Gary Net Worth, Age, Biography, Career, Income, Family, Twitter

Willie E. Gary rose from a common sharecropper son to become one of America’s most popular and influential attorneys. Gary’s rise from poverty to $50 million in net worth is nothing short of inspiring. His tenacity and skills are matched by his extraordinary determination. The movie “The Burial”, starring Jamie Foxx, immortalizes his story as a testament to the American Dream.

Willie E. Gary: Who is he?

Willie Edward Gary was born on July 12, 1947 in Eastman, Georgia. He experienced hardships at a young age. Gary grew up with ten siblings in a sharecropper family. They faced many challenges and slept in tents at times because they did not have a permanent residence. Willie was determined to overcome his situation and earned a law diploma from North Carolina Central University School of Law.

Why is he known as “The Giant Killer?”

Gary’s nickname “The Giant Killer”, is more than just a clever moniker. It’s also a testament to his skill in the courtroom. Gary has won 150 settlements worth millions of dollars for his clients. The Law Firm of Gary, Williams, Parenti, Watson, Gary & Gillespie, P.L.L.C., with over 30 attorneys, is synonymous with landmark verdicts.

What was the $500 million Judgement about?

Gary’s biggest accomplishment is his lawsuit against Loewen Group. This massive funeral home company. Gary obtained a $500 million verdict for a funeral home owner, Jeremiah Joseph O’Keefe. The Burial, the film that details Gary’s amazing victory, is based on this David vs. Goliath battle.

How Does Gary’s Contingency Lawsuit Model Work?

Gary’s firm operates on a contingent basis, which is a unique way to approach legal cases. The firm is only paid if it wins a case. Their cut could range between 30% and 50%, depending on the case. Gary’s confidence and commitment to his clients is reflected in this model.

What financial challenges has Gary faced?

Success is not without obstacles. Gary’s law firm relies on specialized financial companies, like LawFinance Group, to fund the high operational costs of contingency suits. Gary was faced with legal issues in 2012 when LawFinance filed a lawsuit against him for an alleged $10,000,000 high-interest loan.

In 2013, IberiaBank filed a lawsuit and seized $3.2 million in personal property from Gary’s mansion in Sewall Point. The bank claimed Gary and his spouse owed $3.3million in relation to three properties located in Fort Pierce, Florida. Gary is undeterred by these setbacks and remains a force in the legal field.

What is the impact of Willie E. Gary on popular culture?

Gary’s influence extends far beyond the courtroom. Gary has appeared on numerous talk shows, including “The Oprah Winfrey Show.” He was also named to “Ebony’s” “100 Most Important Black Americans” List for 2002. His incredible journey, filled with challenges and victories, is an inspiration to many and a shining example for perseverance and backbone.

Willie E. Gary is a living testament to the spirit of hard work and determination. His journey from the Georgia fields to the elite legal circles in Florida underscores his belief that passion and dedication can help one overcome the most impossible odds.

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Kailyn Lowry Net Worth, Age, Career, Family, Bio, Nationality and Personal Life

Kailyn Lowry is an American reality TV persona, a creator and a public speaker. She has become a household name and thought for many. She has overcome many challenges in her life and continues to inspire thousands of women around the world. This article explores her life, career and achievements.

What is Kailyn lowry?

Kailyn gained national recognition first as a cast member on MTV’s 16 and Pregnant, which featured the lives of teenage mothers. She continued her journey with the spinoff series “Teen Mom 2”, sharing the trials and tribulations she faced as a young mom. Her candor has made her a beacon for desire and advice to many.

What will Kailyn Lowry be worth in 2023?

Kailyn’s net worth in 2023 is estimated at $25,000. This may seem modest for a TV character but it’s important to remember that net worth includes assets and liabilities. Kailyn is still a mother and focuses on her children, advocacy work, and career despite the challenges.

What was Kailyn like in her early years?

Kailyn was born on March 14, 1992 in Honesdale Pennsylvania. Her early years were marred by hardships. She was a young girl who battled depression and anxiety. Her family environment was turbulent. She became pregnant with Isaac at the age of 17. Instead of giving up, she chose to use these demanding situations as motivation and earned her high college diploma or even attended Delaware State University briefly.

What about Kailyn and her family?

Kailyn has four children, Isaac, Lincoln and Lux. She has experienced first-hand all the trials and tribulations of motherhood as a young woman – whether co-parenting with another parent, being single parented herself, or simply loving and raising her own kids on her own. Her love and dedication towards raising them sets an excellent example for all parents everywhere.

Kailyn is proud of her heritage?

Kailyn is proud of her mixed race. She has addressed her challenges and prejudices as an African-American with Puerto Rican roots; but did not allow these to stop her from using her platform to promote diversity and inclusion.

What makes Kailyn a recognized figure in the US

Kailyn was born in Honesdale Pennsylvania but her influence is felt throughout the entire state. From “16 and Pregnant”, to “Teen Mom 2”, her journey has made her a unique figure. Kailyn has also written several works, including “Pride Over Pity”, “A Letter of Love”, and other reality TV shows.

What has Kailyn done with her platform beyond television?

Kailyn’s influence extends beyond reality television. She has written multiple books and spoken at numerous public speaking engagements on mental health, LGBTQ+ rights and women’s empowerment issues.

What are some of the notable achievements in Kailyn’s career?

Although Kailyn is yet to win any awards, the achievements of her large fan base are evident. Her advocacy work, her books’ inspiration, and her unwavering spirit in overcoming personal challenges are all testaments to her achievements.

Kailyn’s life is an example of resilience, determination and the ability to overcome adversity. She is a beacon for hope to many, from her struggles as a young mom to her advocacy of important societal issues. Kailyn’s journey continues to inspire, empower and remind us of our own strength.

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Rupali Barua (Ashish Vidyarthi Wife) Wiki, Bio, Net Worth, Age, Career, & More.

Rupali Barua is a famous Indian fashion designer and celebrity wife, best known as the spouse of renowned Indian actor Ashish Vidyarthi. She is an entrepreneur who runs a fashion boutique in Kolkata named NAMEG.

She has earned a name as a fashion entrepreneur from Guwahati, Assam, with her high-end apparel business in Kolkata. Hard work, talent, and a solid entrepreneurial spirit have all been the hallmarks of her success path. This article will explore Rupali Barua’s biography, age, height, husband, family, career, and net worth.

Early Life and Education

Rupali Barua was welcomed into the world by Ambika Barua and Mrs. Barua on April 21, 1973, in Guwahati, Assam, India. According to her birthday, she was born under the Taurus astrological sign. She is of Indian citizenship and is of white descent. She has always had an interest in fashion and design.

Rupali started her path to becoming a fashion designer after finishing her elementary studies at St. Mary’s Higher Secondary School in Guwahati. After graduating high school, she completed a Bachelor of Arts in Anthropology at Cotton University in Guwahati. She later earned a Master of Arts in Anthropology from Gauhati University in Guwahati.

Quick Wiki/Bio

Full Name Rupali Barua
Gender Female
Age 50 years old
Date of Birth April 21, 1973
Place of Birth Guwahati, Assam, India
Nationality Indian
Zodiac Sign Taurus
Ethnicity White
High School St. Mary’s Higher Secondary School
University Cotton University in Guwahati
Gauhati University in Guwahati
Credentials Master of Arts in Anthropology
Bachelor of Arts in Anthropology

Career

Rupali Barua launched her fashion career in 2005 when she opened her first boutique in Kolkata. Rupali swiftly garnered notoriety for her innovative designs and flawless craftsmanship, thanks to her incredible eye for detail and commitment to creating high-quality clothes. Her business quickly became a popular destination for local and international fashion fans.

Rupali Barua’s business empire increased as her popularity rose, and she opened additional outlets in Kolkata and other major cities across India. Her dedication to offering excellent customer service and her inventive designs cemented her status as the country’s premier fashion entrepreneur.

Later, she relocated to Mumbai, India’s fashion center, to follow her aspirations. Rupali Barua’s modeling career took off after she obtained deals with well-known agencies in Mumbai. She participated in primary fashion weeks and events and walked the runway for renowned fashion designers.

Net Worth

How rich is Rupali Barua? Rupali Barua has earned a great deal of money from her fashion career. As of this writing, Rupali has an estimated net worth of over $1 million, which she earned from her fashion career. Her high-end clothing business and growing industry presence demonstrate her financial success.

Rupali Barua has made significant contributions to the fashion business. Her dedication to perfection and inventive designs have garnered her acclaim and recognition. While specific accolades are not readily available, her success as a fashion entrepreneur demonstrates her talent and determination.

Net Worth $1 million
Salary Under Review
Income Source Fashion

Personal Life

Who is Rupali married to? Rupali Barua is happily married to the famous Indian actor Ashish Vidyarth. The two lovebirds exchanged marriage vows on May 23, 2023. Before she married Ashish, she was married to Rajoshi Vidyarthi, a famous Indian singer.

Marital Status Married
Spouse Ashish Vidyarth
Children Unknown
Hair Color Brown
Eye Color Black
Rupali Barua and Ashish Vidyarth
Instagram @rupalibarua
Twitter @RupaliBarua
TikTok @rupkotharupali

FAQs

Where was Rupali Barua born?

Rupali was born in Guwahati, Assam, India.

What is Rupali Barua’s net worth?

As of this writing, Rupali is worth $1 million.

How old is Rupali Barua?

As of this writing, Rupali is 50 years old.

What is Rupali Barua’s ethnicity?

Rupali Barua is of white ethnicity.

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Biography, Wiki, Boyfriend, Age, Early Life, Career, Net Worth & More

If you are a music lover, especially pop, soul, and R&B, Adele will be famous to you. Adele is known for her powerful and emotional songs. The lyrics of her songs are emotional and express her feelings. 

In this article, you will learn more about Adele’s age, early life, career, net worth, family background, personal life, weight, height, social media presence, and more.

Who is Adele?

Adele is a famous English singer and songwriter best known for her powerful and emotional songs. The singer is recognized worldwide, has won many awards, and has sold many albums globally. Adele is one of the best-selling music artists.

Early Life and family background

Adele Laurie Blue Adkins, popularly known as Adele, was born in Tottenham, London, England, on May 5, 1988. Penny Adkins (English) and Marc Evans (Welsh) are her parents.
When she was two, her father left the family, and her mother raised her all by herself. According to the singer, her mother encouraged her to pursue her dreams, and her mother is her biggest supporter.
She attended a local primary school in Tottenham. She then attended a comprehensive school called Chestnut Grove in Balham, London.
Adele didn’t like traditional classroom settings, so her mother took her to the BRIT School for Performing Arts & Technology in Croydon, South London. She graduated with a diploma in music in 2006.

Quick wiki/Bio

Full Name Adele Laurie Blue Adkins
Nickname Adele
Gender Female
Age 35 years old
Date of Birth May 5, 1988
Place of Birth  Tottenham, London, England
Nationality English
Zodiac Sign Taurus
Ethnicity White
High School Chestnut Grove
University BRIT School for Performing Arts and Technology
Credentials Diploma in Music

Career

Adele began her career at a young age in 2006, when she was signed to a record label, XL Recordings, after graduating from the BRIT School. Her first album was released on November 19, 2008. The album was a hit, and she won two Grammys and other awards for the album.
After her first album debut in 2006, the singer released other albums and singles that were equally great as her first album. Her second album became the best-selling album of the 2010 decade worldwide.
Adele is one of the most successful and famous singers of her generation. The singer and songwriter named her albums after the age she started writing them, for instance, 19, 21, 25, and 30.
She has also won many awards for singing and songwriting, such as 16 Grammy Awards, one Oscar, one Golden Globe, and many more.

Adele’s Net Worth

According to online sources, Adele’s estimated net worth is around $220 million as of 2023. Her primary source of income is music, and she also owns real estate properties in England.

Net Worth $220 million
Salary Under Review
Source of Wealth Music, Real Estate
Profession Singer and songwriter
Adele

Personal Life

Fans of Adele are curious about her personal life, and some of the common questions they ask are: Is Adele married, who is her partner, and many others?

She married Simon Konecki, a charity entrepreneur, in 2018 but divorced in 2021. They have a son named Angelo, who was born in 2012. She is currently dating Rich Paul.

According to her latest interview, the singer said, she is only in love with Rich Paul, but she is not married.
Adele stands 5 feet 9 inches and weighs 139 pounds (63 kg). The singer and songwriter have beautiful light brown hair and green eyes.

Marital status Divorced
Relationship Status In a relationship
Parents Penny Adkins (Mother) and Marc Evans (Father)
Partner George Santo Pietro (m. 1990–2002)
Siblings Unknown
Hair Color Light Brown
Eye Color Green
Fake boobs No
Height 5 feet 9 inches
Weight 139 pounds (63 kg)
Hobbies and Interests Traveling, Internet Surfing, Shopping, Selfie lovers, and dog lovers

Connect with Adele on the following social media platforms:

Instagram @adele
Twitter @Adele
Facebook Adele

FAQs

Here are some frequently asked questions about Adele.

What is the singer’s full name? 

The singer’s full name is Adele Laurie Blue Adkins.

When was she born? 

She was born on May 5, 1988.

Where is Adele from?

 She is from Tottenham, London, England.

What is her musical genre? 

she is a soul and pop singer.

What is Adele’s most famous song?

 Her most popular song is “Rolling in the Deep.”

What albums has Adele released?

She has released four studio albums: 19 (2008), 21 (2011) , 25 (2015), 30 (2021)

What awards has the singer won?

 She won 15 Grammy Awards, 12 BRIT Awards, 1 Academy Award, and 1 Golden Globe Award.

Is Adele married? 

She was married to Simon Konecki from 2018 to 2019. She is currently dating Rich Paul.

What is Adele’s net worth? 

Her net worth is around $220 million as of 2023.

Is Adele still making music? 

Yes, her current studio album was released on November 30, 2021.

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Theo Thompson’s Wiki, biography, birthday, age, height, net worth & updates.

How well do you know Theo Thompson? Theo Thompson is an American celebrity kid, media face, and internet personality born on December 20, 2021. He rose to stardom in the country and worldwide as the renowned son of famous basketball player Tristan Thompson and American model Maralee Nichols. To discover more about Theo Thompson, please continue reading.

Theo Thompson’s Net Worth

How rich is Theo Thompson? Theo Thompson is an American celebrity kid, media face, and internet personality whose net worth is unknown. He rose to fame as the son of famous basketball player Tristan Thompson and American model Maralee Nichols.

Tristan Thompson is a Canadian-American professional basketball player for the National Basketball Association who is a free agent, and Maralee Nichols is an American model. Theo has no net worth because he is too young and has no career to pursue to accumulate it. As a result, he enjoys his parent’s wealth.

Net Worth
Salary
Profession Celebrity Kid and Internet Personality

Early Life

Theo Thompson was welcomed into the world by Tristan Thompson, a Canadian-American professional basketball player, and Maralee Nichols, an American model, on December 20, 2021, in the United States of America. According to her birthday, he was born under the Sagittarius zodiac sign. Thompson was raised in Christianity, is of white ethnicity, and holds American citizenship. In terms of education, there is no record of his education since he is too young. But we will update you as soon as any new data is gathered.

Quick Wiki/Bio

Full Name Theo Thompson
Gender Male
Age 2 years old
Date of Birth December 20, 2021
Place of Birth United States of America
Nationality American
Zodiac Sign Sagittarius
Ethnicity White
High School Unknown
University Unknown
Credentials Unknown

Career

Theo Thompson is still very young and has a long way to go before he can support himself with work or get a job and take care of himself. Because he is less than one year old, his survival likely depends on his parents’ income. He is looking forward to beginning his studies very soon because he does not have a job at the moment.

Personal Life

It is known that the son of the famous basketball player is too young for romantic relationships. He spends most of his time in a stroller or on his parents’ laps, enjoying fun times with his family. There is no record of his body measurements because he is too young.

Marital Status Single
Girlfriend
Children Unknown
Parents Unknown
Siblings True Thompson and Tatum ( half-siblings)
Height Unknown
Weight Unknown
Body Measurement Unknown
Hair Color Brown
Eye Color Brown
Instagram
Twitter
Tik Tok
OnlyFans

FAQs

Where was Theo Thompson born?

Theo was born in the United States of America.

What is Theo Thompson’s net worth?

Currently, Theo Thompson’s net worth is unknown.

How old is Theo Thompson?

As of 2023, Theo Thompson is 2 years old.

What is Verronica Kirei’s ethnicity?

Theo Thompson9 is of white ethnicity.